NATIONAL ACADEMY OF SCIENCES OF TAJIKISTAN

Research Institution “Chinese-Tajik Innovation Center for Natural Products”

Brief information on the history of the establishment of a scientific and research institution - The establishment of the joint center is based on the instructions of the Founder of National Peace and Unity, the Great Leader of the Nation, His Excellency, Honorable Emomali Rahmon, on the processing and production of medicinal products from native medicinal plants.

Research Institute Chinese-Tajik Innovation Center for Natural Products, National Academy of Sciences of Tajikistan was established with access of the agreement on scientific cooperation between the National Academy of Sciences of Tajikistan and the Chinese Academy of Sciences from September 13, 2014, in order to strengthen scientific cooperation and its implementation in the most important areas of fundamental research and applied in the fields of natural and technical sciences and on the basis of the protocol meeting on cooperation from May 4, 2018, between the Xinjiang Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences and the National Academy of Sciences of Tajikistan.

The main areas of scientific activity Research Institute Chinese-Tajik Innovation Center for Natural Products, National Academy of Sciences of Tajikistan are:

1. Study of natural products of the Republic of Tajikistan, including a detailed study of chemical composition, separation and investigation of pharmacological properties of biologically active substances from medicinal plants of the Republic of Tajikistan.

2. Bilateral scientific cooperation and training of highly qualified personnel in the field of chemistry of natural compounds, pharmacology and pharmaceuticals.

Achievements

Phytochemistry and biological activity of secondary metabolites of Hypericum scabrum, Geranium collinum, Anaphalis virgata, Angelica ternate, Artemisia dracunculus L., Artemisia leucotricha, Artemisia annua L., Artemisia vachanica, Prangos pabularia Lindl., Dracocephalum heterophyllum Benth., Cercis griffithii, Helichrysum thianschanicum Regel, Ferula kuhistanica, Hyssopus seravchanicus have been studied and the results of our research have been published in prestigious international scientific journals. Artemisinin (antimalarial substance) was found in seven Artemisia species collected from Tajikistan. The amount of artemisinin in the dry mass of Artemisia species samples was equal to 0.07% to 0.45%. Artemisia vachanica is a new plant source of artemisinin. Alcoholic extracts of Artemisia annua and Artemisia vachanica have shown beneficial effects in the treatment of patients with symptoms of the coronavirus disease COVID-19. The activity of extracts of Hypericum scabrum and Geranium collinum against type 2 diabetes was studied and significant results were obtained.

Inventive activity: The patent of the Republic of Tajikistan No. TJ 1338 (from 18.01.2023; authors Salimov A.M., Sharopov F.S.) was received for the invention of "Oil-in-water nanoemulsion with antibacterial activity".

Numonov S.R. Haji Akber Aisa. Diabetes medicine and preparation method of Gin Guan Cao complex formula. Patent number: CN 201810056079.9 registered in the People's Republic of China.

Application of scientific results in production: All efforts to implement the results of scientific work in the production of biologically active and medicinal products are effective, and intelligent design is being carried out.

Publishing activities: The main works of scientists of the center have been published in more than 50 scientific articles, 1 monograph, and 2 book chapters.

Training of scientific personnel: 4 masters and 5 doctoral students are studying at the National Academy of Sciences of Tajikistan and the Academy of Sciences of China.

Scientific cooperation:

1.Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences. Urumqi, China;

2. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China;

3. Chemical Institute named after V.I. Nikitin of the National Academy of Sciences of Tajikistan

4. Innovative center of new technologies of the National Academy of Sciences of Tajikistan

Outlook: Scientists at our center consider the instructions and calls of the Founder of Peace and National Unity - Leader of the Nation, President of the Republic of Tajikistan Emomali Rahmon on the implementation of the production of medicinal products from domestic medicinal plants as the basis of their work, and are making every effort to introduce domestic medicinal products in the future.